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Headlines added December 2, 2008

Argonne scientists discover possible mechanism for creating 'handedness' in biological molecules
The basic molecules that make up all living things have a predetermined chirality or "handedness," similar to the way people are right or left handed. This chirality has a profound influence on the chemistry and molecular interactions of living organisms. Scientists at the US Department of Energy's Argonne National Laboratory have discovered a way to induce this handedness in pre-biological molecules.  12/2/08
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Headlines added earlier

Proteins' subtle 'backrub' motion could have important implications
Duke University Medical Center | EurekAlert!
Biochemists have detected a surprising, subtle new gyration that protein molecules undergo in the intricate, squirming dance that influences their activity in the cell. The researchers have also created a realistic geometrical model of the twisting "backrub" motion that could help scientists understand the basics of protein function and design proteins for medical use. 2/6/2006
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A clue to core problem of neurodegenerative disease and cell death
Northwestern University | EurekAlert!
Misfolded and damaged proteins are common to all human neurodegenerative diseases, but explanations for the mechanism that kills neurons have varied widely. Northwestern University scientists now offer a clue that may establish a common mechanism in these diseases. Their findings suggest that the disease-associated, aggregation-prone proteins may exert their destabilizing effects by interfering with other proteins that are having difficulty folding, causing them to lose function. Over time, this can cause the organism to die. 2/8/2006
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A new way of looking at molecular motors
Howard Hughes Medical Institute | EurekAlert!
An innovative way of categorizing myosin, one of three molecular motors that produce movement within cells of the body, has dramatically increased the amount of information available about these essential proteins. The new system lays the groundwork for development of treatments for conditions ranging from certain kinds of blindness and kidney disease to neurodegenerative disorders and parasitic diseases such as malaria. 2/8/2006
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Hydrogen bonds shown to play 'conserved' role in protein folding
Duke University | EurekAlert!
By changing individual atoms in key places in proteins, Duke University chemists have found new evidence for the importance of comparatively weak "hydrogen bonds" in enabling stringlike proteins to fold into the maximally stable shape they need to assume their roles as biological workhorses. Such protein folding immediately after proteins are synthesized is central to their function in the cell. 2/9/2006
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When good DNA goes bad
University of Texas M.D. Anderson Cancer Center | EurekAlert!
When otherwise normal DNA adopts an unusual shape called Z-DNA, it can lead to the kind of genetic instability associated with cancers such as leukemia and lymphoma, according to a study by researchers at The University of Texas M. D. Anderson Cancer Center. 2/9/2006
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Brain changes significantly after age 18, says Dartmouth research
Dartmouth College | EurekAlert!
Two Dartmouth researchers are one step closer to defining exactly when human maturity sets in. In a study aimed at identifying how and when a person's brain reaches adulthood, the scientists have learned that, anatomically, significant changes in brain structure continue after age 18. 2/5/2006
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Receptor critical in neurodegeneration reduces Alzheimer's plaque
Yale University \ EurekAlert!
Increasing the level of a protein that plays a key role in traumatic spinal cord injuries and multiple sclerosis reduces the concentration of disease-causing plaque in Alzheimer's disease. 
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MNI researchers find that sense of smell is dependent on body position
McGill University | EurekAlert!
Before giving flowers or scattering rose petals on Valentine's Day, make sure your significant other has already gotten out of bed. In a study published recently in the journal Chemical Senses, researchers at the Montreal Neurological Institute at McGill University discovered that sensitivity to rose odour is greater in subjects that are sitting than in those lying down. 
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New measurements prove myosin VI can act as molecular transporter
University of Illinois at Urbana-Champaign | EurekAlert!
In living organisms, hundreds of different kinds of molecular motors perform a variety of essential, but little understood tasks that result in such actions as muscle contraction, cell division and the movement of materials within cells. Some motors act as transporters, some serve as anchors, and some may do both. 
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Study finds 60 new genes controlled by DNA snippet
University of Rochester Medical Center | EurekAlert!
As part of a nationwide effort to define ancient sections of our genetic code that may soon be as important to medical science as genes, researchers at the University of Rochester Medical Center scanned through the vast human DNA code to reveal for the first time 60 genes influenced by one such sequence, according to an article published today in the journal Genome Research. 
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Omega-6 fats cause prostate tumors to grow twice as fast
University of California - San Francisco | EurekAlert!
Omega-6 fatty acids -- such as those found in corn oil -- caused human prostate tumors in cell culture to grow twice as quickly as tumors to which omega-6 fats had not been added, according to a study conducted at the San Francisco VA Medical Center. 
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Missing steps of jumping-gene replication discovered
University of Pennsylvania School of Medicine | EurekAlert!
In experiments with transgenic mice, University of Pennsylvania School of Medicine researchers discovered the remaining steps in the complicated process of how the largest class of jumping genes replicates and inserts themselves within the human genome. This knowledge may shed light on the origins of "junk" DNA, parts of the genome for which no function has yet been discovered. 
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RNAi and telomere length
Cold Spring Harbor Laboratory | EurekAlert!
A team of Russian scientists, led by Dr. Vladimir Gvozdev (Russian Academy of Sciences) reports on a novel link between RNAi and telomere maintenance in the Drosophila germline. 
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Common molecular 'signature' identified in solid tumors
Ohio State University | EurekAlert!
Scientists have discovered that a wide variety of different cancers actually share something in common - a molecular "signature" made up of tiny bits of genetic material called microRNA (miRNA) that target key cancer genes and promote malignant growth. The finding provides more insight into miRNA as an emerging class of gene regulators and may also pave the way for new approaches in diagnosis and treatment. 
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Hot-spring bacteria flip a metabolic switch
Carnegie Institution | EurekAlert!
Researchers have found that photosynthetic bacteria in scalding Yellowstone hot springs have two radically different metabolic identities: as the sun goes down, these cells quit their day job of photosynthesis and unexpectedly begin to fix nitrogen gas (N2) into biologically useful compounds. They are the first known heat-tolerant organism that can juggle both tasks within a single cell, and the discovery should help to answer longstanding questions about nitrogen metabolism in hot-spring microbial communities. 
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Contagious obesity? Identifying the human adenoviruses that may make us fat
American Physiological Society | EurekAlert!
Accumulating evidence suggests that human adenoviruses viruses may cause obesity, in essence making obesity contagious, according to a study from the University of Wisconsin. The research identified the third such virus that causes obesity in animals, noting that one of these had already been associated with human obesity. More research is needed to test and confirm these results in humans, identify which human adenoviruses could cause obesity, and develop a vaccine, the researchers said. 
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Source of crucial immune cell in the skin discovered
Mount Sinai Hospital / Mount Sinai School of Medicine | EurekAlert!
Mount Sinai researchers have identified the precursors of cells in the skin that are part of the first line of defense against invading pathogens. Known as Langerhans cells, they form a tight network of cells covering the entire body. Many tumor vaccines rely on these cells to activate an immune response. According to the researchers, this discovery should contribute to ongoing efforts to engineer immune responses in vaccine design and tumor immunotherapy. 
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Bacteria in dirt may be "born" resistant to drugs
Maggie Fox | Reuters
WASHINGTON (Reuters) - Bacteria in dirt may be "born" with a resistance to antibiotics, which could help shed light on the problem of drug-defying "superbugs," Canadian researchers said on Thursday.
They tested 480 different bacteria found in soil and discovered that every single one had some resistance to antibiotics -- meaning they had evolved a mechanism for evading the effects of the drugs.
The findings, published in the journal Science, could help explain why bacteria so quickly develop resistance to antibiotics, and why drug companies must constantly develop new ones.     
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The closest look ever at the cell's machines
European Molecular Biology Laboratory | EurekAlert!
Today researchers in Germany announce they have finished the first complete analysis of the "molecular machines" in one of biology's most important model organisms: S. cerevisiae (baker's yeast). The study from the biotechnology company Cellzome, in collaboration with the European Molecular Biology Laboratory (EMBL), appears in this week's online edition of Nature. 

"To carry out their tasks, most proteins work in dynamic complexes that may contain dozens of molecules," says Giulio Superti-Furga, who launched the large-scale project at Cellzome four years ago. "If you think of the cell as a factory floor, up to now, we've known some of the components of a fraction of the machines. That has seriously limited what we know about how cells work. This study gives us a nearly complete parts list of all the machines, and it goes beyond that to tell us how they populate the cell and partition tasks among themselves."    1/21/2006
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Keeping biological tubes in check: New insights into tube size morphogenesis
Cell Press | EurekAlert!
The function of tubular organs like the kidneys, lungs, and vessels of the vascular system is critically dependent on the length and diameter of the tubular branches of which they are composed. Several devastating pathological conditions like polycystic kidney disease and ischemias have been intimately linked to the aberrant sizes of tubular organs. Yet the underlying cellular and molecular mechanisms that control tube size are poorly understood, and, consequently, drugs that intervene in tubular organ disorders are lacking. 
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Reactive oxygen species shown essential for development of inner ear's balance machinery
Cell Press | EurekAlert!
Reactive oxygen species (ROS) are normally produced as a product of metabolism, and, as their name implies, they are highly reactive with surrounding biological components. In an unanticipated discovery suggesting that ROS may play important positive roles in development, researchers have found that the production of ROS by a particular enzyme is essential for inner ear development and for the ability to properly maintain balance. 
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Pair of studies offer new clues to combat antibiotic resistance
American Chemical Society | EurekAlert!
In the continuing battle against antibiotic resistance, two new studies shed light on the complex defense mechanisms pathogenic bacteria use to evade antibiotic attack, an understanding of which could lead to new, more effective antibiotics to help save lives and combat the growing problem of antibiotic resistance. The studies are published in the inaugural issue of ACS Chemical Biology, a monthly peer-reviewed publication of the American Chemical Society. 
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Common bacteria pirate natural mechanism to get inside cells
Medical College of Georgia | EurekAlert!
These pathogens gain entry the same way millions of receptors on the cell's surface routinely do after they get activated, says Dr. Yehia Daaka, professor and Distinguished Chair in Oncologic Pathology at the Medical College of Georgia. Dr. Daaka is corresponding author on an article published Jan. 23 by Proceedings of the National Academy of Sciences.
By moving off the cell surface, receptors gain some respite from their activating signals, Dr. Daaka says. Receptors can either stay inside the newly created vesicle and be degraded or resurface to be activated once again.
Bacteria and viruses also want inside cells and out of the direct line of fire of the immune system or treatments such as antibiotics for bacterial infections, Dr. Daaka says. "Some bacteria and viruses bind to receptors on the plasma membrane and use them to go inside, and that is how they start replicating inside the cell," he says.     
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Patterns in genome organization may partially explain how microbial cells work
University of California - San Diego | EurekAlert!
The location of a piece of real estate may be its most important feature to many Realtors, and bioengineering researchers at the University of California, San Diego (UCSD) and the University of Virginia have reported that the location of genes and other features distributed along the chromosomes of bacteria and simpler organisms also is fundamentally important to how microbial cells operate.
In a paper published Jan. 13 online in PLoS Computational Biology, the researchers reported large- and small-scale organizational patterns in the genomes of 135 bacteria ranging from those that cause typhoid fever and various other human infections to organisms that enrich the nitrogen content of soil. In addition, 16 more primitive microorganisms, including one that thrives in boiling hot springs, also exhibit patterns in their genomes that are highly nonrandom.     
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UCSD biologists find new evidence for one-way evolution
University of California - San Diego | EurekAlert!
By tracing the 30-million year history of variation in a gene found in plants such as tomatoes and tobacco, biologists at the University of California, San Diego have found new evidence to support an old idea -- that some evolutionary changes are irreversible. 

Their study, published this week in an early online edition of the journal Proceedings of the National Academy of Sciences, offers new support for the idea that the loss of complex traits, like eyes, wings or in this case a reproductive mechanism, is often irreversible. In other words, once lost, the traits never revert to their original state.
"This is the strongest evidence yet to support irreversibility," said Joshua Kohn, an associate professor of biology at UCSD who headed the study. "If we had not used the genetic data coding for this reproductive mechanism and only inferred the pattern of evolution based on the traits of living species, we would have come to the opposite conclusion and with high statistical support -- that the trait evolved more than once."     
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Fat overload kills mammalian cells . key culprit identified
Washington University School of Medicine | EurekAlert!
Investigating the harmful health effects of excess fat, researchers at Washington University School of Medicine in St. Louis have identified a protein that triggers death in mammalian cells overloaded with saturated fat.
The internal "skeleton" (in red) of cells is altered by exposure to high fat.
When the researchers halted production of this protein, called EF1A-1, the cells were able to thrive in ordinarily damaging amounts of the saturated fat palmitate, a fat abundant in Western diets. At the same concentration of palmitate, normal cells still producing EF1A-1 rapidly died. The study will be published in the February 2006 issue of Molecular Biology of the Cell.     
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In the mind's eye: How the brain makes a whole out of parts
Johns Hopkins University | EurekAlert!
When a human looks at a number, letter or other shape, neurons in various areas of the brain's visual center respond to different components of that shape, almost instantaneously fitting them together like a puzzle to create an image that the individual then "sees" and understands. 

The question of how the brain sees, recognizes and understands objects is one of the most intriguing in neuroscience, associate professor and paper co-author Charles E. Connor said.
"This may not even seem like a scientific question to some people, because seeing is so automatic and we are so good at it – far better than the best computer vision systems yet devised," Connor said. "That is because a large part of the human brain is devoted to interpreting objects in our world, so that we have the necessary information for interacting with our environment.    
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Tiny RNA molecules fine-tune the brain's synapses
Children's Hospital Boston | EurekAlert
Non-coding regions of the genome – those that don't code for proteins – are now known to include important elements that regulate gene activity. Among those elements are microRNAs, tiny, recently discovered RNA molecules that suppress gene expression. Increasing evidence indicates a role for microRNAs in the developing nervous system, and researchers from Children's Hospital Boston now demonstrate that one microRNA affects the development of synapses – the points of communication between brain cells that underlie learning and memory. The findings appear in the January 19th issue of Nature.
"This paper provides the first evidence that microRNAs have a role at the synapse, allowing for a new level of regulation of gene expression," says senior author Michael Greenberg, PhD, Director of Neuroscience at Children's Hospital Boston. "What we've found is a new mechanism for regulating brain function."      
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Custom-Made Microbes, at Your Service
Andrew Pollack | New York Times
There are bacteria that blink on and off like Christmas tree lights and bacteria that form multicolored patterns of concentric circles resembling an archery target. Yet others can reproduce photographic images.
These are not strange-but-true specimens from nature, but rather the early tinkering of synthetic biologists, scientists who seek to create living machines and biological devices that can perform novel tasks.
"We want to do for biology what Intel does for electronics," said George Church, a professor of genetics at Harvard and a leader in the field. "We want to design and manufacture complicated biological circuitry."   
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Long-term memory controlled by molecular pathway at synapses
Harvard University | EurekAlert!
Harvard University biologists have identified a molecular pathway active in neurons that interacts with RNA to regulate the formation of long-term memory in fruit flies. The same pathway is also found at mammalian synapses, and could eventually present a target for new therapeutics to treat human memory loss. 1/11/2006
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Supersized 'island' of resistance genes discovered in an infectious bacterium
Public Library of Science | EurekAlert!
Researchers have discovered a cluster of 45 genes coding for antibacterial drug resistance in the bacterium, Acinetobacter baumannii, a major cause of hospital-acquired infections worldwide. The study was reported in the open-access journal PLoS Genetics.
"We expected to find resistance genes," said lead author, Pierre-Edouard Fournier, researcher at the Structural and Genomic Information Laboratory at France's National Center for Scientific Research (CNRS). "But the grouping of most of these genes within a single genomic island was totally unexpected." The resistance island--a group of resistance genes clustered close together on a chromosome--is the largest discovered to date.     1/11/2006
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Rockefeller researchers discover a biological clock within a clock
Rockerfeller University | EurekAlert!
Just as a pocket watch requires a complex system of gears and springs to keep it ticking precisely, individual cells have a network of proteins and genes that maintain their own internal clock -- a 24-hour rhythm that, in humans, regulates metabolism, cell division, and hormone production, as well as the wake-sleep cycle. Studying this "circadian" rhythm in fruit flies, which have genes that are similar to our own, scientists have constructed a basic model of how the cellular timekeeper works. But now, a new report in this week's issue of the journal Science turns the old model on its head: By providing a glimpse into living cells, Rockefeller University researchers have uncovered a previously undetected clock inside the circadian clock. The scientists made the finding with a rarely used technique called FRET, which enabled them to follow circadian proteins over an extended period of time and watch the clock as it ticks away in a living cell.
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Research details how a virus hijacks cell signals to cause infection
Children's Hospital of Philadelphia | EurekAlert!
A common virus that causes meningitis and heart inflammation takes a "back door" approach to evade natural barriers, then exploits biological signals to infect human cells. Broadening knowledge of how viruses cause infection, a new study describes elaborate methods that the group B coxsackievirus has evolved to bypass the body's defenses.
"This study helps to explain how group B coxsackieviruses infect cells," said Jeffrey M. Bergelson, M.D., a pediatric infectious diseases specialist at The Children's Hospital of Philadelphia. "We found new steps in the virus life cycle."
Dr. Bergelson's study, co-authored with Carolyn B. Coyne, Ph.D., also of Children's Hospital, appears in the Jan. 13 issue of the journal Cell.
Group B coxsackieviruses (CVBs) are common in people, but usually are defeated by the immune system after causing minor infections. However, CVBs may sometimes cause myocarditis, a potentially severe inflammation of the heart in children and adults, as well as viral meningitis, which inflames the lining of the brain. Rarely, the virus may lead to fatal, overwhelming infection in newborns.    1/11/2006
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Molecule does more than slice and dice RNA
Howard Hughes Medical Institute | EurekAlert!
A team of Howard Hughes Medical Institute (HHMI) scientists has peeled back some of the mystery of how cells are able to turn off genes selectively to control critical events of development. The new insights arise from the first clear molecular images of the structure of Dicer, an enzyme that enables cells to dissect genetic material precisely. 

The finding, which is reported in the January 13, 2005, issue of the journal Science by an HHMI research team at the University of California, Berkeley, provides scientists with new information about a mechanism that enables cells to silence genes, a process that governs key developmental events ranging from brain development to stem cell differentiation.
The study was led by Jennifer A. Doudna, a Howard Hughes Medical Institute investigator at the University of California, Berkeley. Doudna's research team used x-ray crystallography to assemble a detailed three-dimensional picture of an enzyme known as Dicer. In cells, Dicer jumpstarts RNA interference, a process that causes genes to be turned off and which, in turn, prompts a host of key developmental events.  
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Cracking the genetic code for control of gene expression
University of Helsinki | EurekAlert!
Where will a gene be expressed and when? Researchers are now able to predict regions of genomic DNA that will drive gene expression. Molecular biologists, developmental biologists and computer scientists at the University of Helsinki, Finland, came together to advance towards cracking the code for how gene expression is controlled. The results of this work are published in Cell, in January 2006.
Based on the universal code by which DNA encodes amino acids, we can make sense of the constantly increasing amout of DNA sequence data as far as it encodes proteins. This code was solved in 1966 and it has allowed researchers to find new genes and estimate the total number of genes in the human genome. However, coding sequence covers only about 1.2% of the human genome. New codes and grammatical rules need to be resolved in order to understand the remaining 98.8% of the genome. 
It is evident that genes are expressed in tightly controlled spatial and temporal patterns but we do not know the code by which the expression is regulated. In this post-genomic era, the next big goal is to decipher the genetic code of regulation of gene expression.    1/11/2006
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Disgraced cloning scientist 'sorry'
Disgraced South Korean scientist Hwang Woo-suk asks the nation for forgiveness for fabricated research papers. 1/11/2006
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The giant protein titin helps build muscles
European Molecular Biology Laboratory | EurekAlert!
Imagine grabbing two snakes by the tail so that they can't wriggle off in opposite directions. Scientists at the Hamburg Outstation of the European Molecular Biology Laboratory (EMBL) and collaborators from King's College in London have now discovered that something similar happens to a protein that is crucial in the formation of muscle tissue. Their work appears in the current issue of the journal Nature. 

Under the microscope, muscle looks like millions of tiny pistons, stacked end-to-end into long rows. These structures, called sarcomeres, permit the contraction and relaxation of muscle that allow our bodies to move. Sarcomeres are connected at the ends by Z-disks, thick bands of densely-packed molecules. "Sarcomeres are very complex structures, and for many years we've been investigating the steps by which they are formed," says Matthias Wilmanns, Head of the EMBL Hamburg Outstation. "That probably starts when proteins link up to each other in very big assemblies. The meeting point is the Z-disk, but unraveling the connections has been difficult."    1/10/2006
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Hedgehog protein blocks fat production, produces more bone
UT Southwestern Medical Center | EurekAlert!
A protein that guides the early development of creatures as diverse as fruit flies and humans also plays a role in regulating fat and bone formation in adult organisms, researchers at UT Southwestern Medical Center have discovered.
The protein, called hedgehog, activates a series of biochemical reactions involving a host of other cellular proteins and genes. The complex interaction among these many components is called the "hedgehog signaling pathway," and it is critical that the pathway functions properly in the early stages of development of many organisms. Mutations in proteins that make up hedgehog signaling also are involved in some human cancers and other human diseases.
"We found that if you stimulate the hedgehog pathway in fruit flies, fat formation is blocked and the flies are skinny. If we block the pathway, the flies become obese," said Dr. Jonathan Graff, associate professor in the Center for Developmental Biology at UT Southwestern and the study's senior author. "We also found the same effects in mammalian models, specifically, in mouse cells. Activating the hedgehog pathway blocks fat from forming in mammals, while inhibiting the pathway stimulates the creation of more fat cells."      1/9/2006
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Cells That Read Minds
Sandra Blakeslee | New York Times
On a hot summer day 15 years ago in Parma, Italy, a monkey sat in a special laboratory chair waiting for researchers to return from lunch. Thin wires had been implanted in the region of its brain involved in planning and carrying out movements.
Every time the monkey grasped and moved an object, some cells in that brain region would fire, and a monitor would register a sound: brrrrrip, brrrrrip, brrrrrip.
A graduate student entered the lab with an ice cream cone in his hand. The monkey stared at him. Then, something amazing happened: when the student raised the cone to his lips, the monitor sounded - brrrrrip, brrrrrip, brrrrrip - even though the monkey had not moved but had simply observed the student grasping the cone and moving it to his mouth.   
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The unknown world of the stomach
BBC News
A whole unknown community of bacteria makes its home in the human stomach, it has been discovered. 

Scientists had believed that the acid in stomachs made them inhospitable.
But the discovery of the ulcer-causing bacteria H.pylori led Stanford University scientists to explore this undiscovered world.
The Proceedings of the National Academy of Sciences study even found a bacterium related to one previously detected in radioactive waste sites.  "It's quite surprising that they found these bacteria", said Professor Charles Penn, University of Birmingham.    1/8/2006
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In bacterial diversity, Amazon is a 'desert'; Desert is an 'Amazon'
Duke University | EurekAlert!
Ironically, in the diversity of soil bacteria, the otherwise species-rich Amazon is a more like a desert, while the arid desert is a teeming microbial Amazon, researchers have found. Their first-ever continental-scale genetic survey of soil bacteria revealed that the primary factor that seems to govern the diversity of soil bacteria is soil pH. Thus, the acidic soils of topical forests harbor fewer bacterial species than the neutral soils of deserts. 

The researchers said that, since soil bacteria play a fundamental role in a vast array of ecological processes, their survey constitutes an initial step in a new research pathway to understanding that role.
"Although soil bacteria have been studied for centuries, fundamental biological questions remain unanswered," said Fierer. "We probably know more about the organisms in the deepest ocean trenches than we know about the organisms living in soil in our backyards.     
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AIDS drug from sunflowers
University of Bonn | EurekAlert!
Sunflowers can produce a substance which prevents the AIDS pathogen HIV from reproducing, at least in cell cultures. This is the result of research carried out by scientists at the University of Bonn in cooperation with the caesar research centre. For several years now the hopes for a completely new group of AIDS drugs have been pinned to what is known as 'DCQA'. However, the substance is only available in very small quantities and is thus extremely expensive. By using the Bonn method it could probably be produced for a fraction of the costs. The researchers have patented their method. Together with the Jülich Research Centre they now want to attempt to manufacture the substance on a large scale. They are looking for partners in industry to help them with this.
It all began with a small mould with the tongue-twisting name sclerotinia sclerotiorum. The pathogen responsible for the dreaded 'white stem rot' can, if the weather conditions are unfavourable, destroy an entire sunflower crop. However, some sunflowers survive the fungus attack more or less unscathed. They do this by producing specific antibodies which eventually put a stop to the fungus.    1/8/2006
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Loosen leash on cancer protein 'watchdog,' researchers say     1/3/2006   Read whole story

Tandem transcripts team together      1/3/2006    Read whole story

Where 'jumping genes' fear to tread      1/3/2006   Read whole story

Not so different after all: Mysterious eye cells adapt to light     1/3/2006   Read whole story

Little known DNA repair enzyme may be a tumor suppressor gene      1/2/2006   Read whole story

Amid Confusion, Journal Retracts Korean's Stem Cell Paper    12/31/2005    Read whole story

Study finds genes that 'fine-tune' muscle development process     12/28/2005    Read whole story

Study suggests way to re-energize immune response to chronic viral infection     12/27/2005    Read whole story

Natural compound from 'pond scum' shows potential activity against Alzheimer's    12/26/2005   Read whole story

Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds    12/25/2005   Read whole story

Sickle cell disease corrected in human models using stem cell-based gene therapy    12/24/2005   Read whole story

Mechanism for Epstein-Barr virus protein's role in blood cancers discovered     12/22/2005    Read whole story

New study expands understanding of the role of RNA editing in gene control     12/22/2005    Read whole story

A little telomerase isn't enough    12/21/2005   Read whole story

Science's Breakthrough of the Year: Evolution in Action    12/21/2005   Read whole story


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